Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP)
[Edit]DAN16; SCAF6; SR-related CTD-associated factor 6
Calcium Homeostasis Endoplasmic Reticulum ProteinInvolved in calcium homeostasis, growth and proliferation. Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1. CHERP expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle, and in cultured HEL and Dami cells. brain; uncharacterized tissue; lung; lymph node; embryonic tissue; mixed; placenta; prostate; uterus; eye; testis; mammary gland; blood; skin; ovary; liver; thymus; intestine; muscle; adrenal gland; kidney; lymph; heart; bladder; connective tissue; trachea; mouth; pancreas; cervix; thyroid; esophagus; ascites; stomach; spleen; salivary gland; parathyroid; adipose tissue; bone; larynx; nerve
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPF406Hu01 | Recombinant Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAF406Hu01 | Polyclonal Antibody to Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) | ELISA Kit Customized Service Offer |
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract].
- "Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats."Nat. Genet. 14:285-291(1996) [PubMed] [Europe PMC] [Abstract].
- "Cloning of human Ca2+ homoeostasis endoplasmic reticulum protein (CHERP): regulated expression of antisense cDNA depletes CHERP, inhibits intracellular Ca2+ mobilization and decreases cell proliferation."Biochem. J. 348:189-199(2000) [PubMed] [Europe PMC] [Abstract]
- "Ca2+ release by inositol 1,4,5-trisphosphate is blocked by the K(+)-channel blockers apamin and tetrapentylammonium ion, and a monoclonal antibody to a 63 kDa membrane protein: reversal of blockade by K+ ionophores nigericin and valinomycin and purification of the 63 kDa antibody-binding protein."Biochem. J. 300:673-683(1994) [PubMed] [Europe PMC] [Abstract]
- "Antisense-mediated loss of calcium homoeostasis endoplasmic reticulum protein (CHERP; ERPROT213-21) impairs Ca2+ mobilization, nuclear factor of activated T-cells (NFAT) activation and cell proliferation in Jurkat T-lymphocytes."Biochem. J. 373:133-143(2003) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]