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Fatty Acid Desaturase 2 (FADS2)

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LLCDL2; FADSD6; D6D; TU13; DES6; Delta-6-Desaturase; Delta(6) fatty acid desaturase

Fatty Acid Desaturase 2 (FADS2)
CCC F417
HGNC 3575
MGI 1930079
PubMed 23737301
RGD 68339
UniProt O95864
Wiki FADS2
Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. FADS2 is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.It was reported the FADS2 interacts with breastfeeding such that breast-fed children with the "C" version of the gene appear about 7 intelligence quotient (IQ) points higher than those with the less common "G" version .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF417Hu01 Recombinant Fatty Acid Desaturase 2 (FADS2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF417Hu01 Polyclonal Antibody to Fatty Acid Desaturase 2 (FADS2) WB; IHC
MAF417Hu21 Monoclonal Antibody to Fatty Acid Desaturase 2 (FADS2) WB; IHC; ICC; IP.
Assay Kits SEF417Hu ELISA Kit for Fatty Acid Desaturase 2 (FADS2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Fatty Acid Desaturase 2 (FADS2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Fatty Acid Desaturase 2 (FADS2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fatty Acid Desaturase 2 (FADS2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Fatty Acid Desaturase 2 (FADS2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fatty Acid Desaturase 2 (FADS2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF417Ra01 Recombinant Fatty Acid Desaturase 2 (FADS2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF417Ra01 Polyclonal Antibody to Fatty Acid Desaturase 2 (FADS2) WB; IHC; ICC; IP.
MAF417Ra21 Monoclonal Antibody to Fatty Acid Desaturase 2 (FADS2) WB; IHC; ICC; IP.
Assay Kits SEF417Ra ELISA Kit for Fatty Acid Desaturase 2 (FADS2) Enzyme-linked immunosorbent assay for Antigen Detection.
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  2. "cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family."Genomics 66:175-183(2000) [PubMed] [Europe PMC] [Abstract]
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  9. "Identification of the delta-6 desaturase of human sebaceous glands: expression and enzyme activity."J. Invest. Dermatol. 120:707-714(2003) [PubMed] [Europe PMC] [Abstract]
  10. ErratumJ. Invest. Dermatol. 121:434-434(2003)
  11. "Regulation of human delta-6 desaturase gene transcription: identification of a functional direct repeat-1 element."J. Lipid Res. 44:686-695(2003) [PubMed] [Europe PMC] [Abstract]
  12. "Expression of human delta-6-desaturase is associated with aggressiveness of human breast cancer."Int. J. Mol. Med. 12:253-257(2003) [PubMed] [Europe PMC] [Abstract]
  13. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]