Members of the F-box protein family, such as FBXO10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
Jin et al. (2004) reported that the FBXO10 protein contains a central F box and a C-terminal CASH domain, which is found in carbohydrate-binding proteins and sugar hydrolases.
Jin et al. (2004) stated that the FBXO10 gene maps to chromosome 9p13.1 and the mouse Fbxo10 gene maps to chromosome 4B1.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant F-Box Protein 10 (FBXO10) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to F-Box Protein 10 (FBXO10) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to F-Box Protein 10 (FBXO10) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for F-Box Protein 10 (FBXO10) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for F-Box Protein 10 (FBXO10) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant F-Box Protein 10 (FBXO10) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to F-Box Protein 10 (FBXO10) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to F-Box Protein 10 (FBXO10) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for F-Box Protein 10 (FBXO10) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for F-Box Protein 10 (FBXO10) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant F-Box Protein 10 (FBXO10) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to F-Box Protein 10 (FBXO10) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to F-Box Protein 10 (FBXO10) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for F-Box Protein 10 (FBXO10) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for F-Box Protein 10 (FBXO10) | ELISA Kit Customized Service Offer |
- "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "A family of mammalian F-box proteins."Curr. Biol. 9:1180-1182(1999) [PubMed] [Europe PMC] [Abstract]
- "Identification of a family of human F-box proteins."Curr. Biol. 9:1177-1179(1999) [PubMed] [Europe PMC] [Abstract]
- "Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma."Proc. Natl. Acad. Sci. U.S.A. 110:3943-3948(2013) [PubMed] [Europe PMC] [Abstract]
- "DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation."Dev. Cell 28:697-710(2014) [PubMed] [Europe PMC] [Abstract]