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Tetraspanin 6 (TSPAN6)

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T245; TM4SF6; Transmembrane 4 Superfamily Member 6; Putative NF-kappa-B-activating protein 321; Tetraspanin TM4-D; T245 protein; A15 homolog

Tetraspanin 6 (TSPAN6)
CCC F436
HGNC 11858
MGI 1926264
PubMed 22908223
RGD 1560160
UniProt O43657
Wiki TSPAN6
Tetraspanin-6 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The TM4SF6 protein contains 4 putative transmembrane domains, several short cysteine motifs characteristic of TM4SF proteins, and a potential N-glycosylation site. The TM4SF6 and TM4SF2 proteins are 58% homologous. TM4SF6 was expressed as 1.9- and 1.3-kb transcripts in all human tissues examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetraspanin 6 (TSPAN6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetraspanin 6 (TSPAN6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetraspanin 6 (TSPAN6) Polyclonal Antibody Customized Service Offer
Assay Kits SEF436Hu ELISA Kit for Tetraspanin 6 (TSPAN6) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetraspanin 6 (TSPAN6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetraspanin 6 (TSPAN6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetraspanin 6 (TSPAN6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tetraspanin 6 (TSPAN6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tetraspanin 6 (TSPAN6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tetraspanin 6 (TSPAN6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tetraspanin 6 (TSPAN6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tetraspanin 6 (TSPAN6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tetraspanin 6 (TSPAN6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tetraspanin 6 (TSPAN6) ELISA Kit Customized Service Offer
  1. "Sequences and expression of six new members of the tetraspanin/TM4SF family."Biochim. Biophys. Acta 1399:101-104(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and characterization of a novel human gene, TM4SF6, encoding a protein belonging to the transmembrane 4 superfamily, and mapped to Xq22."Genomics 52:240-242(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways."Oncogene 22:3307-3318(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]