≡

Centaurin Beta 2 (CENTb2)

[Edit]

ACAP2; Arf-GAP With Coiled-Coil,ANK Repeat And PH Domain-Containing Protein 2

Centaurin Beta 2 (CENTb2)
CCC F463
HGNC 16469
MGI 1925868
PubMed 11050434
RGD 1562939
UniProt Q15057
Wiki CENTB2
The 3-prime untranslated region of the CENTB2 mRNA contains an Alu repeat. CENTB2 shares 52% sequence identity with CENTB1 and about 28% identity with ankyrin. Northern blot analysis revealed ubiquitous expression, with highest levels detected in peripheral blood leukocytes, followed by placenta, kidney, spleen, and ovary. Lowest levels were detected in brain.The deduced 778-amino acid protein contains 2 N-terminal coiled-coil regions, a pleckstrin homology (PH) domain, an ARF-GAP domain, and C-terminal ankyrin repeats. ACAP2 shares significant similarity with CENTB1, which the authors called ACAP1, and 95% identity with mouse Acap2. It also shares similarity with ASAP1 and PAP in the ARF-GAP domain and in the overall domain structure.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centaurin Beta 2 (CENTb2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centaurin Beta 2 (CENTb2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centaurin Beta 2 (CENTb2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centaurin Beta 2 (CENTb2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centaurin Beta 2 (CENTb2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centaurin Beta 2 (CENTb2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centaurin Beta 2 (CENTb2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centaurin Beta 2 (CENTb2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centaurin Beta 2 (CENTb2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centaurin Beta 2 (CENTb2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centaurin Beta 2 (CENTb2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centaurin Beta 2 (CENTb2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centaurin Beta 2 (CENTb2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centaurin Beta 2 (CENTb2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centaurin Beta 2 (CENTb2) ELISA Kit Customized Service Offer
  1. "ACAPs are arf6 GTPase-activating proteins that function in the cell periphery."J. Cell Biol. 151:627-638(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 1:223-229(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  12. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]