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Junctophilin 3 (JPH3)

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CAGL237; HDL2; JP-3; JP3; TNRC22; Trinucleotide Repeat Containing 22

Junctophilin 3 (JPH3)
CCC F489
HGNC 14203
MGI 1891497
PubMed 21555070
RGD 1308416
UniProt Q8WXH2
Wiki JPH3
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels.
Junctophilin-3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF489Hu01 Recombinant Junctophilin 3 (JPH3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Junctophilin 3 (JPH3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Junctophilin 3 (JPH3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Junctophilin 3 (JPH3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Junctophilin 3 (JPH3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF489Mu01 Recombinant Junctophilin 3 (JPH3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Junctophilin 3 (JPH3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Junctophilin 3 (JPH3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Junctophilin 3 (JPH3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Junctophilin 3 (JPH3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Junctophilin 3 (JPH3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Junctophilin 3 (JPH3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Junctophilin 3 (JPH3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Junctophilin 3 (JPH3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Junctophilin 3 (JPH3) ELISA Kit Customized Service Offer
  1. "Characterization of human junctophilin subtype genes."Biochem. Biophys. Res. Commun. 273:920-927(2000) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease-like 2."Nat. Genet. 29:377-378(2001) [PubMed] [Europe PMC] [Abstract]
  4. "CAG/CTG repeat expansions at the Huntington's disease-like 2 locus are rare in Huntington's disease patients."Neurology 58:965-967(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Huntington's disease-like 2 can present as chorea-acanthocytosis."Neurology 61:1002-1004(2003) [PubMed] [Europe PMC] [Abstract]