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Janus Kinase 3 (JAK3)

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JAKL; L-JAK; LJAK; A Protein Tyrosine Kinase,Leukocyte; Leukocyte janus kinase; Tyrosine-protein kinase JAK3

Janus Kinase 3 (JAK3)
CCC F493
HGNC 6193
MGI 99928
PubMed 8921370
RGD 2940
UniProt P52333
Wiki JAK3
JAK3 encodes Janus kinase 3, a tyrosine kinase that belongs to the Janus family. JAK3 functions in signal transduction and interacts with members of the STAT (signal transduction and activators of transcription) family. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Since JAK3 expression is restricted mostly to hematopoietic cells, its role in cytokine signaling is thought to be more restricted than other JAKs. It is most commonly expressed in T cells and NK cells, but has been induced in other leukocytes, including monocytes. Jak3 is involved in signal transduction by receptors that employ the common gamma chain (γC) of the type I cytokine receptor family .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF493Hu01 Recombinant Janus Kinase 3 (JAK3) Positive Control; Immunogen; SDS-PAGE; WB.
APF493Hu01 Active Janus Kinase 3 (JAK3) Cell culture; Activity Assays.
Antibodies PAF493Hu01 Polyclonal Antibody to Janus Kinase 3 (JAK3) WB; IHC; ICC; IP.
MAF493Hu21 Monoclonal Antibody to Janus Kinase 3 (JAK3) WB; IHC; ICC; IP.
Assay Kits SEF493Hu ELISA Kit for Janus Kinase 3 (JAK3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF493Mu01 Recombinant Janus Kinase 3 (JAK3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF493Mu01 Polyclonal Antibody to Janus Kinase 3 (JAK3) WB
Assay Kits n/a CLIA Kit for Janus Kinase 3 (JAK3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Janus Kinase 3 (JAK3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF493Ra01 Recombinant Janus Kinase 3 (JAK3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF493Ra01 Polyclonal Antibody to Janus Kinase 3 (JAK3) WB; IHC; ICC; IP.
MAF493Ra21 Monoclonal Antibody to Janus Kinase 3 (JAK3) WB; IHC; ICC; IP.
Assay Kits SEF493Ra ELISA Kit for Janus Kinase 3 (JAK3) Enzyme-linked immunosorbent assay for Antigen Detection.
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