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Kinesin Family, Member 5C (KIF5C)

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NKHC2; Kinesin heavy chain neuron-specific 2

Kinesin Family, Member 5C (KIF5C)
CCC F508
HGNC 6325
MGI 1098269
PubMed 20094756
RGD 1308539
UniProt O60282
Wiki KIF5C
By screening human brain cDNAs for the potential to encode proteins larger than 100 kD, Nagase et al. (1998) isolated a full-length KIF5C cDNA, which they called KIAA0531.
The deduced 957-amino acid KIF5C protein shares 75.4% amino acid sequence identity with KIF5A across 953 amino acids. By SDS-PAGE, in vitro transcribed/translated KIF5C has an apparent molecular mass greater than 100 kD. RT-PCR detected KIF5C expression in several human tissues, with the highest expression in brain, prostate, and testis, and moderate expression in kidney, small intestine, and ovary. By radiation hybrid mapping, Nagase et al. (1998) mapped the KIF5C gene to chromosome 2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 5C (KIF5C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 5C (KIF5C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 5C (KIF5C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 5C (KIF5C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 5C (KIF5C) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 5C (KIF5C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 5C (KIF5C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 5C (KIF5C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 5C (KIF5C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 5C (KIF5C) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 5C (KIF5C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 5C (KIF5C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 5C (KIF5C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 5C (KIF5C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 5C (KIF5C) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin."Hum. Mol. Genet. 6:2205-2212(1997) [PubMed] [Europe PMC] [Abstract]
  5. "GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin."J. Biol. Chem. 280:14723-14732(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "Diagnostic exome sequencing in persons with severe intellectual disability."N. Engl. J. Med. 367:1921-1929(2012) [PubMed] [Europe PMC] [Abstract]
  8. "Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly." Nat. Genet. 45:639-647(2013) [PubMed] [Europe PMC] [Abstract]