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Kinesin Family, Member 7 (KIF7)

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Kinesin-like protein KIF7

Kinesin Family, Member 7 (KIF7)
CCC F509
HGNC 30497
MGI 1098239
PubMed 21552264
UniProt Q2M1P5
By database searching using Drosophila Cos2 and mouse Kif7 as probes, Katoh and Katoh (2004) identified full-length KIF7. The deduced 1,343-amino protein shares 43.6% amino acid identity with KIF27 (611253) and 61.6% identity with KIF27 over the kinesin motor domain.
Katoh and Katoh (2004) determined that the KIF7 gene contains at least 19 exons.By genomic sequence analysis, Katoh and Katoh (2004) mapped the KIF7 gene to chromosome 15q26.1.
KIF7 and KIF27 also share an additional region of high homology, which the authors called the KIF7-KIF27 homologous (KIF727H) domain. EST database analysis showed KIF7 mRNA expression in embryonic stem cells, melanotic melanoma, and Jurkat T cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 7 (KIF7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 7 (KIF7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 7 (KIF7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 7 (KIF7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 7 (KIF7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 7 (KIF7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 7 (KIF7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 7 (KIF7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 7 (KIF7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 7 (KIF7) ELISA Kit Customized Service Offer
  1. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Characterization of KIF7 gene in silico."Int. J. Oncol. 25:1881-1886(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development."Curr. Biol. 19:1320-1326(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics."J. Clin. Invest. 121:2662-2667(2011) [PubMed] [Europe PMC] [Abstract]
  10. "KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes." Nat. Genet. 43:601-606(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Novel KIF7 mutations extend the phenotypic spectrum of acrocallosal syndrome."J. Med. Genet. 49:713-720(2012) [PubMed] [Europe PMC] [Abstract]
  12. "A mutation in KIF7 is responsible for the autosomal recessive syndrome of macrocephaly, multiple epiphyseal dysplasia and distinctive facial appearance."Orphanet J. Rare Dis. 7:27-27(2012) [PubMed] [Europe PMC] [Abstract]