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The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
LMNB1 encodes a deduced 586-amino acid protein with a calculated molecular mass of 66,334 Da. The LMNB1 protein shares approximately 72% sequence similarity with lamin A/C.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF548Mi01 | Recombinant Lamin B1 (LMNB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPF548Hu01 | Recombinant Lamin B1 (LMNB1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAF548Mi01 | Polyclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. |
| PAF548Hu01 | Polyclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. | |
| CAF548Hu22 | Anti-Lamin B1 (LMNB1) Monoclonal Antibody | Loading Control of WB | |
| CAF548Hu01 | Anti-Lamin B1 (LMNB1) Polyclonal Antibody | Loading Control of WB | |
| MAF548Hu21 | Monoclonal Antibody to Lamin B1 (LMNB1) | Loading Control of WB; IHC; ICC; IP. | |
| CAF548Mi22 | Anti-Lamin B1 (LMNB1) Monoclonal Antibody | Loading Control of WB | |
| MAF548Hu22 | Monoclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. | |
| MAF548Hu23 | Monoclonal Antibody to Lamin B1 (LMNB1) | WB | |
| MAF548Hu24 | Monoclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. | |
| MAF548Hu25 | Monoclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. | |
| MAF548Hu26 | Monoclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. | |
| MAF548Hu28 | Monoclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEF548Mi | ELISA Kit for Lamin B1 (LMNB1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF548Mi01 | Recombinant Lamin B1 (LMNB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAF548Mi01 | Polyclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. |
| PAF548Mu01 | Polyclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. | |
| CAF548Mi22 | Anti-Lamin B1 (LMNB1) Monoclonal Antibody | Loading Control of WB | |
| Assay Kits | SEF548Mi | ELISA Kit for Lamin B1 (LMNB1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF548Mi01 | Recombinant Lamin B1 (LMNB1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAF548Mi01 | Polyclonal Antibody to Lamin B1 (LMNB1) | WB; IHC; ICC; IP. |
| CAF548Mi22 | Anti-Lamin B1 (LMNB1) Monoclonal Antibody | Loading Control of WB | |
| Assay Kits | SEF548Mi | ELISA Kit for Lamin B1 (LMNB1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "In vitro posttranslational modification of lamin B cloned from a human T-cell line."Mol. Cell. Biol. 10:2164-2175(1990) [PubMed] [Europe PMC] [Abstract]
- "Structural organization of the human gene (LMNB1) encoding nuclear lamin B1."Genomics 27:230-236(1995) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]