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Vesicle Associated Membrane Protein 8 (VAMP8)

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EDB; VAMP5; endobrevin

Vesicle Associated Membrane Protein 8 (VAMP8)
CCC F568
HGNC 12647
MGI 1336882
PubMed 15133481
RGD 620421
UniProt Q9BV40
Wiki VAMP8
VAMP8 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. It is associated with the perinuclear vesicular structures of the early endocytic compartment.
It has been found that VAMP8 interacts specifically with the soluble NSF-attachment protein (alpha-SNAP), most likely through an VAMP8-containing SNARE complex.The deduced 101-amino acid protein contains an amphipathic helix that may participate in coiled-coil interactions and a C-terminal hydrophobic domain predicted to serve as a membrane anchor. Transfection of Vamp8 into normal rat kidney cells resulted in broadly distributed puncta throughout the cell with a juxtanuclear enrichment.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF568Hu01 Recombinant Vesicle Associated Membrane Protein 8 (VAMP8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Vesicle Associated Membrane Protein 8 (VAMP8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vesicle Associated Membrane Protein 8 (VAMP8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vesicle Associated Membrane Protein 8 (VAMP8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vesicle Associated Membrane Protein 8 (VAMP8) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vesicle Associated Membrane Protein 8 (VAMP8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vesicle Associated Membrane Protein 8 (VAMP8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vesicle Associated Membrane Protein 8 (VAMP8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vesicle Associated Membrane Protein 8 (VAMP8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vesicle Associated Membrane Protein 8 (VAMP8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vesicle Associated Membrane Protein 8 (VAMP8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vesicle Associated Membrane Protein 8 (VAMP8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vesicle Associated Membrane Protein 8 (VAMP8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vesicle Associated Membrane Protein 8 (VAMP8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vesicle Associated Membrane Protein 8 (VAMP8) ELISA Kit Customized Service Offer
  1. "Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome."Mol. Biol. Cell 9:1549-1563(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion."Blood 100:1081-1083(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes."Cell 151:1256-1269(2012) [PubMed] [Europe PMC] [Abstract]
  8. "ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes."Nature 0:0-0(2015) [PubMed] [Europe PMC] [Abstract]