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Melanocortin receptor 5 is located on the chromosome 18 in the human genome. when the melanocortin 5 receptor was disrupted in transgenic mice, it induced disruption of their exocrine glands and resulted in decreased production of sebum. Melanocortin-1 receptor (MC1R) is found in melanocytes and appears to be the alpha-melanocyte stimulating hormone (MSH) receptor. MC2R is localized to adrenocortical cells and is thus thought to be the ACTH receptor. MC3R and MC4R are localized primarily to sites in the brain. Each receptor has a unique pattern of affinity for the various melanocortin ligands. Gantz et al. (1994) reported the molecular cloning of a novel gene encoding a fifth member of the MCR family in the mouse. Chowdhary et al. (1995) mapped the human MC5R gene to 18p11.2 by fluorescence in situ hybridization.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF605Hu01 | Recombinant Melanocortin 5 Receptor (MC5R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAF605Hu01 | Polyclonal Antibody to Melanocortin 5 Receptor (MC5R) | WB; IHC; ICC; IP. |
| MAF605Hu21 | Monoclonal Antibody to Melanocortin 5 Receptor (MC5R) | WB; IHC; ICC; IP. | |
| Assay Kits | SEF605Hu | ELISA Kit for Melanocortin 5 Receptor (MC5R) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCF605Hu | CLIA Kit for Melanocortin 5 Receptor (MC5R) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Melanocortin 5 Receptor (MC5R) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Melanocortin 5 Receptor (MC5R) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Melanocortin 5 Receptor (MC5R) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Melanocortin 5 Receptor (MC5R) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Melanocortin 5 Receptor (MC5R) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Melanocortin 5 Receptor (MC5R) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Melanocortin 5 Receptor (MC5R) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Melanocortin 5 Receptor (MC5R) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Melanocortin 5 Receptor (MC5R) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Melanocortin 5 Receptor (MC5R) | ELISA Kit Customized Service Offer |
Organism species: Chicken (Gallus)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF605Ga01 | Recombinant Melanocortin 5 Receptor (MC5R) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Melanocortin 5 Receptor (MC5R) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Melanocortin 5 Receptor (MC5R) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Melanocortin 5 Receptor (MC5R) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Melanocortin 5 Receptor (MC5R) | ELISA Kit Customized Service Offer |
- "Molecular cloning of a novel human melanocortin receptor."Biochem. Biophys. Res. Commun. 195:866-873(1993) [PubMed] [Europe PMC] [Abstract]
- "Molecular cloning and characterization of the rat fifth melanocortin receptor."Biochem. Biophys. Res. Commun. 200:1007-1014(1994) [PubMed] [Europe PMC] [Abstract]
- "Cloning, expression, and tissue distribution of a fifth melanocortin receptor subtype."Neurochem. Res. 20:107-113(1995) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Glutamine235 and arginine272 in human melanocortin 5 receptor determines its low affinity to MSH."Biochem. Biophys. Res. Commun. 236:489-492(1997) [PubMed] [Europe PMC] [Abstract]
- "Expression, candidate gene, and population studies of the melanocortin 5 receptor."J. Invest. Dermatol. 116:564-570(2001) [PubMed] [Europe PMC] [Abstract]