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Myotubularin Related Protein 6 (MTMR6)

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Myotubularin Related Protein 6 (MTMR6)
CCC F606
HGNC 7453
MGI 2145637
PubMed 19038970
RGD 1305378
UniProt Q9Y217
Wiki MTMR6
Mutations in the myotubularin (MTM1) dual-specific phosphatase gene cause X-linked myotubular myopathy. By searching an EST database for sequences related to MTM1, Laporte et al. (1998) identified a partial MTMR6 (myotubularin-related protein-6) cDNA and cDNAs encoding 3 other novel members of the myotubularin protein family.
Sequence comparisons of the predicted protein-tyrosine phosphatase/dual-specificity phosphatase region of myotubularin family members indicated that MTMR6, MTMR7, a Drosophila gene, and a nematode gene form a distinct subgroup. Northern blot analysis revealed that the 4.8-kb MTMR6 mRNA is expressed ubiquitously.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myotubularin Related Protein 6 (MTMR6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myotubularin Related Protein 6 (MTMR6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myotubularin Related Protein 6 (MTMR6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myotubularin Related Protein 6 (MTMR6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myotubularin Related Protein 6 (MTMR6) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myotubularin Related Protein 6 (MTMR6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myotubularin Related Protein 6 (MTMR6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myotubularin Related Protein 6 (MTMR6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myotubularin Related Protein 6 (MTMR6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myotubularin Related Protein 6 (MTMR6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myotubularin Related Protein 6 (MTMR6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myotubularin Related Protein 6 (MTMR6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myotubularin Related Protein 6 (MTMR6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myotubularin Related Protein 6 (MTMR6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myotubularin Related Protein 6 (MTMR6) ELISA Kit Customized Service Offer
  1. "Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9."Proc. Natl. Acad. Sci. U.S.A. 100:9768-9773(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human."Hum. Mol. Genet. 7:1703-1712(1998) [PubMed] [Europe PMC] [Abstract]
  7. "The phosphatidylinositol 3-phosphate phosphatase myotubularin-related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1."Mol. Cell. Biol. 25:3630-3638(2005) [PubMed] [Europe PMC] [Abstract]
  8. "Systematic analysis of myotubularins: heteromeric interactions, subcellular localisation and endosome related functions."J. Cell Sci. 119:2953-2959(2006) [PubMed] [Europe PMC] [Abstract]
  9. "Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells."Mol. Cell. Biol. 26:5595-5602(2006) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Human ALKBH4 interacts with proteins associated with transcription."PLoS ONE 7:E49045-E49045(2012) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]