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Myotubularin Related Protein 3 (MTMR3)

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FYVE-DSP1; ZFYVE10; FYVE domain-containing dual specificity protein phosphatase 1; Phosphatidylinositol-3-phosphate phosphatase; Zinc finger FYVE domain-containing 10

Myotubularin Related Protein 3 (MTMR3)
CCC F613
HGNC 7451
MGI 1921552
PubMed 23154468
RGD 1310972
UniProt Q13615
Wiki MTMR3
Myotubularin-related protein 3 is a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myotubularin Related Protein 3 (MTMR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myotubularin Related Protein 3 (MTMR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myotubularin Related Protein 3 (MTMR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myotubularin Related Protein 3 (MTMR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myotubularin Related Protein 3 (MTMR3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myotubularin Related Protein 3 (MTMR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myotubularin Related Protein 3 (MTMR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myotubularin Related Protein 3 (MTMR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myotubularin Related Protein 3 (MTMR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myotubularin Related Protein 3 (MTMR3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myotubularin Related Protein 3 (MTMR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myotubularin Related Protein 3 (MTMR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myotubularin Related Protein 3 (MTMR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myotubularin Related Protein 3 (MTMR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myotubularin Related Protein 3 (MTMR3) ELISA Kit Customized Service Offer
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  8. "Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity."Curr. Biol. 11:1600-1605(2001) [PubMed] [Europe PMC] [Abstract]
  9. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]