≡

Retinoic Acid Induced Protein 14 (RAI14)

[Edit]

NORPEG; RAI13; Ankycorbin; Novel Retinal Pigment Epithelial; Novel retinal pigment epithelial cell protein; Ankyrin repeat and coiled-coil structure-containing protein

Retinoic Acid Induced Protein 14 (RAI14)
CCC F766
HGNC 14873
MGI 1922896
PubMed 23565266
RGD 1305942
UniProt Q9P0K7
Wiki RAI14
Human RAI14 has a predicted molecular mass of 110 kD, a pI of 5.83, 6 potential N-glycosylation sites, several ankyrin repeats, and several coiled-coil helical domains. Like the ARPE-19 cells, placenta showed an intense signal at 5 kb and a weak signal at 3 kb; the reverse was observed in testis, with an intense signal at 3 kb and a weak signal at 5 kb. RAI14 was also highly expressed in several human cancer cell lines. Confocal microscopic analysis in ARPE-19 cells showed threadlike projections in the cytoplasm reminiscent of the cytoskeleton. The expression of Rai14 was detected in mouse embryo at embryonic day 9.5 by in situ hybridization, and the expression appeared to be developmentally regulated. In adult mouse, the highest level of expression was detected in the seminiferous tubules of testis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinoic Acid Induced Protein 14 (RAI14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinoic Acid Induced Protein 14 (RAI14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinoic Acid Induced Protein 14 (RAI14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinoic Acid Induced Protein 14 (RAI14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinoic Acid Induced Protein 14 (RAI14) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinoic Acid Induced Protein 14 (RAI14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinoic Acid Induced Protein 14 (RAI14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinoic Acid Induced Protein 14 (RAI14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinoic Acid Induced Protein 14 (RAI14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinoic Acid Induced Protein 14 (RAI14) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinoic Acid Induced Protein 14 (RAI14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinoic Acid Induced Protein 14 (RAI14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinoic Acid Induced Protein 14 (RAI14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinoic Acid Induced Protein 14 (RAI14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinoic Acid Induced Protein 14 (RAI14) ELISA Kit Customized Service Offer
  1. "Molecular characterization and developmental expression of NORPEG, a novel gene induced by retinoic acid."J. Biol. Chem. 276:2831-2840(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of a novel alternative transcript of the novel retinal pigment epithelial cell gene NORPEG in human testes."Asian J. Androl. 7:277-288(2005) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  8. "Ankycorbin: a novel actin cytoskeleton-associated protein."Genes Cells 5:1001-1008(2000) [PubMed] [Europe PMC] [Abstract]
  9. "Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein."Biochem. Biophys. Res. Commun. 345:1333-1341(2006) [PubMed] [Europe PMC] [Abstract]
  10. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  11. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  16. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]