≡

Anoctamin 3 (ANO3)

[Edit]

TMEM16C; C11orf25; Transmembrane Protein 16C(Eight Membrane-Spanning Domains)

Anoctamin 3 (ANO3)
CCC F798
HGNC 14004
MGI 3613666
PubMed 23200863
RGD 1308873
UniProt Q9BYT9
Wiki ANO3
Anoctamin 3 belongs to the anoctamin family.May act as a calcium-activated chloride channel.Membrane; Multi-pass membrane protein
By database searching with the sequence of TMEM16A as query, Katoh and Katoh (2003) identified TMEM16C. The deduced 981-amino acid TMEM16B protein shares 38.3% sequence identity with TMEM16A. Like TMEM16A, TMEM16C contains 8 potential transmembrane regions with the N- and C-terminal tails facing the cytoplasm and an N-linked glycosylation site in the fourth extracellular loop.By sequence analysis, Katoh and Katoh (2003) mapped the TMEM16C gene to chromosome 11p14.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Anoctamin 3 (ANO3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Anoctamin 3 (ANO3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Anoctamin 3 (ANO3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Anoctamin 3 (ANO3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Anoctamin 3 (ANO3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Anoctamin 3 (ANO3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Anoctamin 3 (ANO3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Anoctamin 3 (ANO3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Anoctamin 3 (ANO3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Anoctamin 3 (ANO3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Anoctamin 3 (ANO3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Anoctamin 3 (ANO3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Anoctamin 3 (ANO3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Anoctamin 3 (ANO3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Anoctamin 3 (ANO3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  3. "Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?"Acta Pharmacol. Sin. 32:685-692(2011) [PubMed] [Europe PMC] [Abstract]
  4. "Anoctamins."Pflugers Arch. 462:195-208(2011) [PubMed] [Europe PMC] [Abstract]
  5. "Mutations in ANO3 cause dominant craniocervical dystonia: ion channel implicated in pathogenesis."Am. J. Hum. Genet. 91:1041-1050(2012) [PubMed] [Europe PMC] [Abstract]
  6. "The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age."Exp. Physiol. 97:175-176(2012) [PubMed] [Europe PMC] [Abstract]
  7. "The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels."Exp. Physiol. 97:177-183(2012) [PubMed] [Europe PMC] [Abstract]