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Taste Receptor Type 2 Member 50 (TAS2R50)

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T2R51

Taste Receptor Type 2 Member 50 (TAS2R50)
CCC F810
HGNC 18882
PubMed 22192511
UniProt P59544
Wiki TAS2R50
TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway .
By screening the human genome for sequences related to TAS2Rs, Conte et al. (2002) cloned TAS2R50, which they called TAS2R51.
The deduced 299-amino acid protein contains the 7-transmembrane structure and short N- and C-terminal domains conserved in TAS2Rs. The intracellular domains share significant conservation with other TAS2R family members.By somatic cell hybrid and genomic sequence analyses, Conte et al. (2002) mapped the TAS2R50 gene to a 1.2-Mb TAS2R gene cluster on chromosome 12p.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Taste Receptor Type 2 Member 50 (TAS2R50) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Taste Receptor Type 2 Member 50 (TAS2R50) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Taste Receptor Type 2 Member 50 (TAS2R50) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Taste Receptor Type 2 Member 50 (TAS2R50) CLIA Kit Customized Service Offer
n/a ELISA Kit for Taste Receptor Type 2 Member 50 (TAS2R50) ELISA Kit Customized Service Offer
  1. "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides."Nat. Genet. 32:397-401(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Identification and characterization of human taste receptor genes belonging to the TAS2R family."Cytogenet. Genome Res. 98:45-53(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Evolution of bitter taste receptors in humans and apes."Mol. Biol. Evol. 22:432-436(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Receptors for bitter and sweet taste."Curr. Opin. Neurobiol. 12:366-371(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Molecular mechanisms of bitter and sweet taste transduction."J. Biol. Chem. 277:1-4(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways."Cell 112:293-301(2003) [PubMed] [Europe PMC] [Abstract]