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Secretogranin III (SCG3)

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SGIII

Secretogranin III (SCG3)
CCC F860
HGNC 13707
MGI 103032
PubMed 21796137
RGD 621209
UniProt Q8WXD2
Wiki SCG3
Secretogranin III is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown.
The deduced 468-amino acid protein, which has a calculated molecular mass of 53 kD, contains an N-terminal signal peptide, a secretogranin motif, 3 potential N-glycosylation sites, and a putative tyrosine sulfation site. SCG3 shares 87%, 87%, and 56% overall identity with the mouse, rat, and Xenopus orthologs, respectively. SCG3 localized to the perinuclear endoplasmic reticulum in transfected COS-7 cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF860Hu01 Recombinant Secretogranin III (SCG3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF860Hu01 Polyclonal Antibody to Secretogranin III (SCG3) WB; IHC; ICC; IP.
MAF860Hu21 Monoclonal Antibody to Secretogranin III (SCG3) WB; IHC; ICC; IP.
Assay Kits SEF860Hu ELISA Kit for Secretogranin III (SCG3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Secretogranin III (SCG3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Secretogranin III (SCG3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Secretogranin III (SCG3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Secretogranin III (SCG3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Secretogranin III (SCG3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Secretogranin III (SCG3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Secretogranin III (SCG3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Secretogranin III (SCG3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Secretogranin III (SCG3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Secretogranin III (SCG3) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of a novel human secretory protein: secretogranin III."Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 34:411-417(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity." J. Clin. Endocrinol. Metab. 92:1145-1154(2007) [PubMed] [Europe PMC] [Abstract]
  7. "LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins."J. Proteome Res. 12:573-584(2013) [PubMed] [Europe PMC] [Abstract]