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Syntrophin Beta 2 (SNTb2)

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SNT2B2; SNT3; SNTL; Dystrophin-Associated Protein A1,59kDa,Basic Component 2; Syntrophin-3; Syntrophin-like

Syntrophin Beta 2 (SNTb2)
CCC F886
HGNC 11169
MGI 101771
PubMed 10404183
RGD 1592340
UniProt Q13425
Wiki SNTB2
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The syntrophins are a family of five 60-kiloDalton proteins that are associated with dystrophin, the protein associated with Duchenne muscular dystrophy and Becker muscular dystrophy. The name comes from the Greek word syntrophos, meaning "companion." The five syntrophins are encoded by separate genes and are termed α, β1, β2, γ1, and γ2.
SNTb2 is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Syntrophin Beta 2 (SNTb2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Syntrophin Beta 2 (SNTb2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Syntrophin Beta 2 (SNTb2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Syntrophin Beta 2 (SNTb2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Syntrophin Beta 2 (SNTb2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Syntrophin Beta 2 (SNTb2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Syntrophin Beta 2 (SNTb2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Syntrophin Beta 2 (SNTb2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Syntrophin Beta 2 (SNTb2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Syntrophin Beta 2 (SNTb2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Syntrophin Beta 2 (SNTb2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Syntrophin Beta 2 (SNTb2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Syntrophin Beta 2 (SNTb2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Syntrophin Beta 2 (SNTb2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Syntrophin Beta 2 (SNTb2) ELISA Kit Customized Service Offer
  1. "The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives."J. Biol. Chem. 271:2724-2730(1996) [PubMed] [Europe PMC] [Abstract]
  2. "The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells."Eur. J. Cell Biol. 79:621-630(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses."Proc. Natl. Acad. Sci. U.S.A. 97:3596-3601(2000) [PubMed] [Europe PMC] [Abstract]
  5. "Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion."EMBO J. 20:4013-4023(2001) [PubMed] [Europe PMC] [Abstract]
  6. "An unappreciated role for RNA surveillance."Genome Biol. 5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  16. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]