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Deleted In Azoospermia Associated Protein 2 (DAZAP2)

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DAZ-associated protein 2

Deleted In Azoospermia Associated Protein 2 (DAZAP2)
CCC F969
HGNC 2684
MGI 1344344
PubMed 22792345
UniProt Q15038
Wiki DAZAP2
DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles.
The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Deleted In Azoospermia Associated Protein 2 (DAZAP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Deleted In Azoospermia Associated Protein 2 (DAZAP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Deleted In Azoospermia Associated Protein 2 (DAZAP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Deleted In Azoospermia Associated Protein 2 (DAZAP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Deleted In Azoospermia Associated Protein 2 (DAZAP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Deleted In Azoospermia Associated Protein 2 (DAZAP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Deleted In Azoospermia Associated Protein 2 (DAZAP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Deleted In Azoospermia Associated Protein 2 (DAZAP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Deleted In Azoospermia Associated Protein 2 (DAZAP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Deleted In Azoospermia Associated Protein 2 (DAZAP2) ELISA Kit Customized Service Offer
  1. "Molecular features and expression of DAZAP2 in human multiple myeloma."Chin. Med. J. 120:1659-1665(2007) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 1:223-229(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1."Genomics 65:266-273(2000) [PubMed] [Europe PMC] [Abstract]
  7. "Characterizing the neurite outgrowth inhibitory effect of Mani."FEBS Lett. 586:3018-3023(2012) [PubMed] [Europe PMC] [Abstract]
  8. "Smurf2 regulates IL17RB by proteasomal degradation of its novel binding partner DAZAP2."Immunobiology 217:321-328(2012) [PubMed] [Europe PMC] [Abstract]