GABRe belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants encoding different isoforms have been identified.
The structure of the 5-prime region of most cDNAs is compatible with expression of GABRE in adult brain only, whereas in other tissues, most transcripts code for truncated protein sequences.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPG027Hu01 | Recombinant Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPG027Hu02 | Recombinant Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | n/a | Monoclonal Antibody to Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Gamma-Aminobutyric Acid A Receptor Epsilon (gABRe) | ELISA Kit Customized Service Offer |
- "Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit."Nature 385:820-823(1997) [PubMed] [Europe PMC] [Abstract]
- "A gene in human chromosome band Xq28 (GABRE) defines a putative new subunit class of the GABAA neurotransmitter receptor."Genomics 45:1-10(1997) [PubMed] [Europe PMC] [Abstract]
- "An mRNA encoding a putative GABA-gated chloride channel is expressed in the human cardiac conduction system."J. Neurochem. 68:1382-1389(1997) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]