≡

Purinergic Receptor P2Y, G Protein Coupled 8 (P2RY8)

[Edit]

P2Y8; P2Y Purinoceptor 8

Purinergic Receptor P2Y, G Protein Coupled 8 (P2RY8)
CCC G081
HGNC 15524
PubMed 20378752
UniProt Q86VZ1
Wiki P2RY8
P2RY8 is a member of the purine nucleotide G protein-coupled receptor gene family and is located in the pseudoautosomal region of the X chromosome .
P2RY8 encodes a deduced 359-amino acid protein.P2RY8 is highly expressed in lymphocytes. Weaker expression was seen in heart, kidney, and lung. Granulocytic differentiation was induced by dimethylsulfoxide, and a monocytic/macrophage phenotype was induced by phorbol esters. Moderate P2Y8 expression was detected in undifferentiated cells, and expression was completely downregulated during granulocyte differentiation. P2Y8 transcription decreased until 24 hours of monocytic differentiation, then began to return to higher levels. P2Y8 expression was barely detectable in normal blood leukocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Purinergic Receptor P2Y, G Protein Coupled 8 (P2RY8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Purinergic Receptor P2Y, G Protein Coupled 8 (P2RY8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Purinergic Receptor P2Y, G Protein Coupled 8 (P2RY8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Purinergic Receptor P2Y, G Protein Coupled 8 (P2RY8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Purinergic Receptor P2Y, G Protein Coupled 8 (P2RY8) ELISA Kit Customized Service Offer
  1. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells."Biochim. Biophys. Acta 1492:127-138(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Disruption of a new X linked gene highly expressed in brain in a family with two mentally retarded males."J. Med. Genet. 41:736-742(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]