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K-Acetyltransferase 2B (KAT2B)

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PCAF; P/CAF; GCN5; GCN5L; P300/CBP-Associated Factor; Histone acetyltransferase PCAF; Lysine acetyltransferase 2B

K-Acetyltransferase 2B (KAT2B)
CCC G189
HGNC 8638
MGI 1343094
PubMed 24051374
UniProt Q92831
Wiki PCAF
Several domains of PCAF can act independently or in unison to enable its functions. PCAF has separate acetyltransferase and E3 ubiquitin ligase domains as well as a bromodomain for interaction with other proteins. PCAF also possesses sites for its own acetylation and ubiquitination.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by the PCAF gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG189Hu01 Recombinant K-Acetyltransferase 2B (KAT2B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG189Hu01 Polyclonal Antibody to K-Acetyltransferase 2B (KAT2B) WB; IHC; ICC; IP.
Assay Kits SEG189Hu ELISA Kit for K-Acetyltransferase 2B (KAT2B) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant K-Acetyltransferase 2B (KAT2B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to K-Acetyltransferase 2B (KAT2B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to K-Acetyltransferase 2B (KAT2B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for K-Acetyltransferase 2B (KAT2B) CLIA Kit Customized Service Offer
n/a ELISA Kit for K-Acetyltransferase 2B (KAT2B) ELISA Kit Customized Service Offer
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