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Forkhead Box Protein K2 (FOXK2)

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FOX-K2; ILF; ILF-1; ILF1; Interleukin Enhancer Binding Factor 1; Cellular transcription factor ILF-1

Forkhead Box Protein K2 (FOXK2)
CCC G228
HGNC 6036
MGI 1916087
PubMed 20810654
RGD 1305408
UniProt Q01167
Wiki FOXK2
Forkhead Box K2(FOXK2)contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements.
Li et al. (1991) cloned ILF from both HeLa and Jurkat cDNA libraries. Further analysis of demonstrated the existence of 2 mRNA species, both of which encode proteins containing the forkhead DNA-binding domain (Li et al., 1992).Li et al. (1991) found that ILF bound to purine-rich regulatory motifs in the HIV-1 long terminal repeat and to the interleukin-2 (IL2; 147680) promoter.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Forkhead Box Protein K2 (FOXK2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Forkhead Box Protein K2 (FOXK2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Forkhead Box Protein K2 (FOXK2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Forkhead Box Protein K2 (FOXK2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Forkhead Box Protein K2 (FOXK2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Forkhead Box Protein K2 (FOXK2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Forkhead Box Protein K2 (FOXK2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Forkhead Box Protein K2 (FOXK2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Forkhead Box Protein K2 (FOXK2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Forkhead Box Protein K2 (FOXK2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Forkhead Box Protein K2 (FOXK2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Forkhead Box Protein K2 (FOXK2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Forkhead Box Protein K2 (FOXK2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Forkhead Box Protein K2 (FOXK2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Forkhead Box Protein K2 (FOXK2) ELISA Kit Customized Service Offer
  1. "Cloning of a cellular factor, interleukin binding factor, that binds to NFAT-like motifs in the human immunodeficiency virus long terminal repeat."Proc. Natl. Acad. Sci. U.S.A. 88:7739-7743(1991) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein ILF."Genomics 13:665-671(1992) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  5. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  12. "Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a)."Proteins 49:543-553(2002) [PubMed] [Europe PMC] [Abstract]
  13. "Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins."J. Biol. Chem. 281:17400-17409(2006) [PubMed] [Europe PMC] [Abstract]