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Forkhead Box Protein N2 (FOXN2)

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FOX-N2; HTLF; Human T-Cell Leukemia Virus Enhancer Factor

Forkhead Box Protein N2 (FOXN2)
CCC G232
HGNC 5281
MGI 1347478
PubMed 21303847
UniProt P32314
A region of the human T-cell leukemia virus long terminal repeat located between -155 and -117 is important in the regulation of gene expression by the ETS family of transcription factors.
By analysis of a panel of mouse-human somatic cell hybrids varying in human chromosome content and by radioactive in situ hybridization, they mapped the HTLF gene to 2p22-p16. The HTLF gene is distinct from another 'forkhead' domain DNA binding protein, ILF, which is localized to chromosome 17q25. Since the ETS1 gene is located on 11q23 and since translocations between 2p22-p16 and 11q23 have been observed in leukemia, it is possible that fusions between portions of the ETS1 and HTLF genes are a mechanism of leukemogenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Forkhead Box Protein N2 (FOXN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Forkhead Box Protein N2 (FOXN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Forkhead Box Protein N2 (FOXN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Forkhead Box Protein N2 (FOXN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Forkhead Box Protein N2 (FOXN2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Forkhead Box Protein N2 (FOXN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Forkhead Box Protein N2 (FOXN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Forkhead Box Protein N2 (FOXN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Forkhead Box Protein N2 (FOXN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Forkhead Box Protein N2 (FOXN2) ELISA Kit Customized Service Offer
  1. "Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein HTLF."Genomics 13:658-664(1992) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]