≡

Proteasome Subunit Alpha Type 6 (PSMa6)

[Edit]

IOTA; PROS27; p27K; 27 kDa prosomal protein; Macropain iota chain; Proteasome iota chain; Multicatalytic endopeptidase complex iota chain

Proteasome Subunit Alpha Type 6 (PSMa6)
CCC G261
HGNC 9535
MGI 1347006
PubMed 16845397
RGD 61849
UniProt P60900
Wiki PSMA6
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Proteasome Subunit Alpha Type 6 is a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG261Hu01 Recombinant Proteasome Subunit Alpha Type 6 (PSMa6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Proteasome Subunit Alpha Type 6 (PSMa6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome Subunit Alpha Type 6 (PSMa6) Polyclonal Antibody Customized Service Offer
Assay Kits SEG261Hu ELISA Kit for Proteasome Subunit Alpha Type 6 (PSMa6) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome Subunit Alpha Type 6 (PSMa6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome Subunit Alpha Type 6 (PSMa6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome Subunit Alpha Type 6 (PSMa6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome Subunit Alpha Type 6 (PSMa6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome Subunit Alpha Type 6 (PSMa6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome Subunit Alpha Type 6 (PSMa6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome Subunit Alpha Type 6 (PSMa6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome Subunit Alpha Type 6 (PSMa6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome Subunit Alpha Type 6 (PSMa6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome Subunit Alpha Type 6 (PSMa6) ELISA Kit Customized Service Offer
  1. "The prosomal RNA-binding protein p27K is a member of the alpha-type human prosomal gene family."Mol. Gen. Genet. 237:193-205(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]