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Proteasome 26S Subunit, ATPase 4 (PSMC4)

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S6; TBP7; Protease 26S subunit 6; MB67-interacting protein; Tat-Binding Protein 7; MB67 Interacting Protein; 26S proteasome AAA-ATPase subunit RPT3

Proteasome 26S Subunit, ATPase 4 (PSMC4)
CCC G274
HGNC 9551
MGI 1346093
PubMed 21979464
RGD 621102
UniProt P43686
Wiki PSMC4
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.
PSMC4 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG274Hu01 Recombinant Proteasome 26S Subunit, ATPase 4 (PSMC4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG274Hu01 Polyclonal Antibody to Proteasome 26S Subunit, ATPase 4 (PSMC4) WB
Assay Kits n/a CLIA Kit for Proteasome 26S Subunit, ATPase 4 (PSMC4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome 26S Subunit, ATPase 4 (PSMC4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome 26S Subunit, ATPase 4 (PSMC4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome 26S Subunit, ATPase 4 (PSMC4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome 26S Subunit, ATPase 4 (PSMC4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome 26S Subunit, ATPase 4 (PSMC4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome 26S Subunit, ATPase 4 (PSMC4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome 26S Subunit, ATPase 4 (PSMC4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome 26S Subunit, ATPase 4 (PSMC4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome 26S Subunit, ATPase 4 (PSMC4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome 26S Subunit, ATPase 4 (PSMC4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome 26S Subunit, ATPase 4 (PSMC4) ELISA Kit Customized Service Offer
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  20. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  21. "Structure of the oncoprotein gankyrin in complex with S6 ATPase of the 26S proteasome."Structure 15:179-189(2007) [PubMed] [Europe PMC] [Abstract]