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Selenium Binding Protein 1 (SELENBP1)

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LPSB; SP56; hSBP; hSP56; SBP56; 56 kDa selenium-binding protein

Selenium Binding Protein 1 (SELENBP1)
CCC G326
HGNC 10719
MGI 96825
PubMed 20615253
RGD 620571
UniProt Q13228
Wiki SELENBP1
protein belongs to the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. It has been proposed that the effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins. The exact function of this gene is not known.
Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG326Hu01 Recombinant Selenium Binding Protein 1 (SELENBP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG326Hu01 Polyclonal Antibody to Selenium Binding Protein 1 (SELENBP1) WB; IHC; ICC; IP.
MAG326Hu21 Monoclonal Antibody to Selenium Binding Protein 1 (SELENBP1) WB; IHC; ICC; IP.
Assay Kits SEG326Hu ELISA Kit for Selenium Binding Protein 1 (SELENBP1) Enzyme-linked immunosorbent assay for Antigen Detection.
AEG326Hu ELISA Kit for Anti-Selenium Binding Protein 1 Antibody (Anti-SELENBP1) Enzyme-linked immunosorbent assay for Antibody Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Selenium Binding Protein 1 (SELENBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Selenium Binding Protein 1 (SELENBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Selenium Binding Protein 1 (SELENBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Selenium Binding Protein 1 (SELENBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Selenium Binding Protein 1 (SELENBP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Selenium Binding Protein 1 (SELENBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Selenium Binding Protein 1 (SELENBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Selenium Binding Protein 1 (SELENBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Selenium Binding Protein 1 (SELENBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Selenium Binding Protein 1 (SELENBP1) ELISA Kit Customized Service Offer
  1. "Isolation, characterization, and chromosomal mapping of a novel cDNA clone encoding human selenium binding protein."J. Cell. Biochem. 64:217-224(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. , Submitted (MAR-2007) to UniProtKB
  6. "Differential expression and androgen regulation of the human selenium-binding protein gene hSP56 in prostate cancer cells."Cancer Res. 58:3150-3153(1998) [PubMed] [Europe PMC] [Abstract]
  7. "Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas."J. Pathol. 202:321-329(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia."Proc. Natl. Acad. Sci. U.S.A. 102:15533-15538(2005) [PubMed] [Europe PMC] [Abstract]
  9. "Selenium binding protein 1 in ovarian cancer."Int. J. Cancer 118:2433-2440(2006) [PubMed] [Europe PMC] [Abstract]
  10. "Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival."Proteomics 6:3466-3476(2006) [PubMed] [Europe PMC] [Abstract]
  11. "Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner."Biochem. Biophys. Res. Commun. 379:583-588(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]