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Sex Determining Region Y Box Protein 4 (SOX4)

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EVI16; Transcription factor SOX-4

Sex Determining Region Y Box Protein 4 (SOX4)
CCC G340
HGNC 11200
MGI 98366
PubMed 23764001
RGD 1309488
UniProt Q06945
Wiki SOX4
SOX4 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate.SOX4 may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin).
The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.Sox4 is expressed in lymphocytes (B and T) and is required for B lymphocyte development.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sex Determining Region Y Box Protein 4 (SOX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sex Determining Region Y Box Protein 4 (SOX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sex Determining Region Y Box Protein 4 (SOX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sex Determining Region Y Box Protein 4 (SOX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sex Determining Region Y Box Protein 4 (SOX4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG340Mu01 Recombinant Sex Determining Region Y Box Protein 4 (SOX4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAG340Mu21 Monoclonal Antibody to Sex Determining Region Y Box Protein 4 (SOX4) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Sex Determining Region Y Box Protein 4 (SOX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sex Determining Region Y Box Protein 4 (SOX4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sex Determining Region Y Box Protein 4 (SOX4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sex Determining Region Y Box Protein 4 (SOX4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sex Determining Region Y Box Protein 4 (SOX4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sex Determining Region Y Box Protein 4 (SOX4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sex Determining Region Y Box Protein 4 (SOX4) ELISA Kit Customized Service Offer
  1. "Characterization and mapping of the human SOX4 gene."Mamm. Genome 4:577-584(1993) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A conserved family of genes related to the testis determining gene, SRY."Nucleic Acids Res. 20:2887-2887(1992) [PubMed] [Europe PMC] [Abstract]
  5. "Ubc9 interacts with SOX4 and represses its transcriptional activity."Biochem. Biophys. Res. Commun. 344:727-734(2006) [PubMed] [Europe PMC] [Abstract]