≡

ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2)

[Edit]

ATP6IP2; CAPER; ELDF10; XMRE; Renin/prorenin receptor; Embryonic liver differentiation factor 10; Vacuolar ATP synthase membrane sector-associated protein M8-9

ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2)
CCC G393
HGNC 18305
MGI 1917745
PubMed 23595882
RGD 1561269
UniProt O75787
Wiki ATP6AP2
ATP6AP2 is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. This protein has been found associated with the transmembrane sector of the V-type ATPases.Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG393Hu01 Recombinant ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG393Hu01 Polyclonal Antibody to ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) WB; IHC; ICC; IP.
Assay Kits SEG393Hu ELISA Kit for ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG393Ra01 Recombinant ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG393Ra01 Polyclonal Antibody to ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) WB; IHC; ICC; IP.
MAG393Ra21 Monoclonal Antibody to ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) WB; IHC; ICC; IP.
Assay Kits SEG393Ra ELISA Kit for ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin."J. Clin. Invest. 109:1417-1427(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  8. "Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules."J. Biol. Chem. 273:10939-10947(1998) [PubMed] [Europe PMC] [Abstract]
  9. "A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor."Hum. Mol. Genet. 14:1019-1027(2005) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS)."Hum. Mol. Genet. 22:3259-3268(2013) [PubMed] [Europe PMC] [Abstract]