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ATPase Class V Type 10A (ATP10A)

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ATP10C; ATPVA; ATPVC; Probable Phospholipid-Transporting ATPase VA; Aminophospholipid translocase VA; P4-ATPase flippase complex alpha subunit ATP10A

ATPase Class V Type 10A (ATP10A)
CCC G404
HGNC 13542
MGI 1330809
PubMed 12782135
RGD 1306150
UniProt O60312
Wiki ATP10A
ATP10A belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene is maternally expressed. It maps within the most common interval of deletion responsible for Angelman syndrome, also known as 'happy puppet syndrome'.
Nagase et al. (1998) isolated a partial cDNA from brain encoding ATP10C, which they called KIAA0566. Based on homology analysis, they predicted that ATP10C is a probable calcium-transporting ATPase. RT-PCR analysis detected wide expression, with highest levels in kidney, followed by lung, brain, prostate, testis, ovary, and small intestine.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
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Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Class V Type 10A (ATP10A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Class V Type 10A (ATP10A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Class V Type 10A (ATP10A) Polyclonal Antibody Customized Service Offer
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Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase Class V Type 10A (ATP10A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase Class V Type 10A (ATP10A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase Class V Type 10A (ATP10A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATPase Class V Type 10A (ATP10A) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATPase Class V Type 10A (ATP10A) ELISA Kit Customized Service Offer
  1. "A novel maternally expressed gene, ATP10C, encodes a putative aminophospholipid translocase associated with Angelman syndrome."Nat. Genet. 28:19-20(2001) [PubMed] [Europe PMC] [Abstract]
  2. "The human aminophospholipid-transporting ATPase gene ATP10C maps adjacent to UBE3A and exhibits similar imprinted expression."Am. J. Hum. Genet. 68:1501-1505(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
  6. "ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner."J. Biol. Chem. 286:38159-38167(2011) [PubMed] [Europe PMC] [Abstract]