Calbindin (CALB)
[Edit]CAB27; Calbindin 1,28kDa; Calbindin D28; Vitamin D-dependent calcium-binding protein, avian-type
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Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted.
The sequence showed an open reading frame coding for a protein of 261 amino acids, containing 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The preliminary data suggested that the 29-kD protein in brain is encoded by a different gene.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG438Hu01 | Recombinant Calbindin (CALB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAG438Hu01 | Polyclonal Antibody to Calbindin (CALB) | WB; IHC; ICC; IP. |
| MAG438Hu21 | Monoclonal Antibody to Calbindin (CALB) | WB | |
| MAG438Hu22 | Monoclonal Antibody to Calbindin (CALB) | WB | |
| MAG438Hu23 | Monoclonal Antibody to Calbindin (CALB) | WB | |
| MAG438Hu24 | Monoclonal Antibody to Calbindin (CALB) | WB | |
| Assay Kits | SEG438Hu | ELISA Kit for Calbindin (CALB) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG438Mu01 | Recombinant Calbindin (CALB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAG438Mu01 | Polyclonal Antibody to Calbindin (CALB) | WB; IHC; ICC; IP. |
| Assay Kits | SEG438Mu | ELISA Kit for Calbindin (CALB) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG438Ra01 | Recombinant Calbindin (CALB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAG438Ra01 | Polyclonal Antibody to Calbindin (CALB) | WB; IHC; ICC; IP. |
| LAG438Ra71 | Biotin-Linked Polyclonal Antibody to Calbindin (CALB) | WB; IHC; ICC. | |
| MAG438Ra21 | Monoclonal Antibody to Calbindin (CALB) | WB; IHC; ICC; IP. | |
| Assay Kits | SEG438Ra | ELISA Kit for Calbindin (CALB) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The human calbindin 27-kDa gene: structural organization of the 5' and 3' regions, chromosomal assignment, and restriction fragment length polymorphism."Genomics 4:309-319(1989) [PubMed] [Europe PMC] [Abstract]
- "Calbindin D28K interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy."Biochem. Biophys. Res. Commun. 303:1186-1192(2003) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]