≡

Growth Arrest Specific Protein 7 (GAS7)

[Edit]

Growth Arrest Specific Protein 7 (GAS7)
CCC G482
HGNC 4169
MGI 1202388
PubMed 23840221
RGD 621550
UniProt O60861
Wiki GAS7
Growth arrest-specific (GAS) genes are expressed preferentially in cells that enter a quiescent state. The gene had originally been identified in serum-starved murine fibroblasts.
GAS7 transcripts encode a 48-kD protein containing a structural domain that resembles sequences of OCT2, a POU transcription factor implicated in neuronal development, and synapsins, e.g., synapsin I (SYN1), which have a role in modulating neurotransmitter release. Conversely, GAS7 overexpression in undifferentiated neuroblastoma cell cultures dramatically promotes neurite-like outgrowth. Collectively, the results provided evidence for an association between expression of GAS7 and neuronal development.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG482Hu01 Recombinant Growth Arrest Specific Protein 7 (GAS7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Growth Arrest Specific Protein 7 (GAS7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Growth Arrest Specific Protein 7 (GAS7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Growth Arrest Specific Protein 7 (GAS7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Growth Arrest Specific Protein 7 (GAS7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG482Mu01 Recombinant Growth Arrest Specific Protein 7 (GAS7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Growth Arrest Specific Protein 7 (GAS7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Growth Arrest Specific Protein 7 (GAS7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Growth Arrest Specific Protein 7 (GAS7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Growth Arrest Specific Protein 7 (GAS7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Growth Arrest Specific Protein 7 (GAS7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Growth Arrest Specific Protein 7 (GAS7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Growth Arrest Specific Protein 7 (GAS7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Growth Arrest Specific Protein 7 (GAS7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Growth Arrest Specific Protein 7 (GAS7) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 4:307-313(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors."Proc. Natl. Acad. Sci. U.S.A. 97:2814-2819(2000) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7."Submitted (OCT-2007) to the PDB data bank