Myelin And Lymphocyte Protein 2 (MAL2)
[Edit]MAL Proteolipid Protein 2; Mal,T-Cell Differentiation Protein 2
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MAL2 encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface.
MAL2 encodes a deduced 176-amino acid protein with 4 transmembrane domains and a (Q/Y)GWVM(F/Y) sequence found in all known MAL-like sequences. The MAL2 protein shares 35.8% sequence identity with MAL, a proteolipid required in apical vesicle transport, and 34.5% with BENE.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Myelin And Lymphocyte Protein 2 (MAL2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Myelin And Lymphocyte Protein 2 (MAL2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Myelin And Lymphocyte Protein 2 (MAL2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Myelin And Lymphocyte Protein 2 (MAL2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Myelin And Lymphocyte Protein 2 (MAL2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Myelin And Lymphocyte Protein 2 (MAL2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Myelin And Lymphocyte Protein 2 (MAL2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Myelin And Lymphocyte Protein 2 (MAL2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Myelin And Lymphocyte Protein 2 (MAL2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Myelin And Lymphocyte Protein 2 (MAL2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Myelin And Lymphocyte Protein 2 (MAL2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Myelin And Lymphocyte Protein 2 (MAL2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Myelin And Lymphocyte Protein 2 (MAL2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Myelin And Lymphocyte Protein 2 (MAL2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Myelin And Lymphocyte Protein 2 (MAL2) | ELISA Kit Customized Service Offer |
- "Identification of MAL2, a novel member of the mal proteolipid family, though interactions with TPD52-like proteins in the yeast two-hybrid system."Genomics 76:81-88(2001) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "MAL2, a novel raft protein of the MAL family, is an essential component of the machinery for transcytosis in hepatoma HepG2 cells."J. Cell Biol. 159:37-44(2002) [PubMed] [Europe PMC] [Abstract]
- "Expression and distribution of MAL2, an essential element of the machinery for basolateral-to-apical transcytosis, in human thyroid epithelial cells."Endocrinology 145:1011-1016(2004) [PubMed] [Europe PMC] [Abstract]
- "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]