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Phosphatidylcholine Transfer Protein (PCTP)

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STARD2; StAR-Related Lipid Transfer(START)Domain Containing 2; StAR-related lipid transfer protein 2

Phosphatidylcholine Transfer Protein (PCTP)
CCC G509
HGNC 8752
MGI 107375
PubMed 7391000
RGD 3276
UniProt Q9UKL6
Wiki PCTP
Phosphatidylcholine (PC) transfer protein (PCTP) is a cytosolic protein first purified from bovine and rat liver that catalyzes intermembrane transfer of PC. By searching an EST database for homologs of bovine Pctp, followed by 5-prime RACE and PCR of a kidney cDNA library, Cohen et al. (1999) obtained a cDNA encoding human PCTP.
The deduced 214-amino acid human protein is 76% and 80% identical to bovine and rat Pctp, respectively. Northern blot analysis revealed wide expression of an approximately 2.3-kb PCTP transcript in all tissues tested except thymus. Highest expression was detected in liver, placenta, testis, kidney, and heart, and lowest levels were found in brain and lung.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylcholine Transfer Protein (PCTP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylcholine Transfer Protein (PCTP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylcholine Transfer Protein (PCTP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylcholine Transfer Protein (PCTP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylcholine Transfer Protein (PCTP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylcholine Transfer Protein (PCTP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylcholine Transfer Protein (PCTP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylcholine Transfer Protein (PCTP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylcholine Transfer Protein (PCTP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylcholine Transfer Protein (PCTP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphatidylcholine Transfer Protein (PCTP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylcholine Transfer Protein (PCTP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylcholine Transfer Protein (PCTP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylcholine Transfer Protein (PCTP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylcholine Transfer Protein (PCTP) ELISA Kit Customized Service Offer
  1. "Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein."Biochim. Biophys. Acta 1447:265-270(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Mice without phosphatidylcholine transfer protein have no defects in the secretion of PC into bile or into the lung airspaces."Proc. Natl. Acad. Sci. U.S.A. 96:11501-11506(1999) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  7. "Human phosphatidylcholine transfer protein: purification, crystallization and preliminary X-ray diffraction data."Biochim. Biophys. Acta 1596:1-5(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Structure of human phosphatidylcholine transfer protein in complex with its ligand."Nat. Struct. Biol. 9:507-511(2002) [PubMed] [Europe PMC] [Abstract]