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Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1)

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Anamorsin; Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog

Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1)
CCC G517
HGNC 28050
MGI 1922083
PubMed 22713669
RGD 1549737
UniProt Q6FI81
Wiki CIAPIN1
CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 or CASP families. Expression of CIAPIN1 is dependent on growth factor stimulation. The predicted 310-amino acid mouse protein has a calculated molecular mass of 37 kD and contains an N-terminal methyltransferase motif. Human and mouse Anamorsin share 82% amino acid identity. Northern blot analysis of human tissues revealed ubiquitous expression of Anamorsin, with particularly high levels in heart, liver, and pancreas. Immunofluorescence microscopy of mouse cells demonstrated that Anamorsin was localized in the cytoplasm exclusively.Addition of growth factors, such as EPO, SCF, TPO, or IL3, all of which depend on RAS signaling, induced dose-dependent expression of Anamorsin in mouse cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytokine Induced Apoptosis Inhibitor 1 (CIAPIN1) ELISA Kit Customized Service Offer
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  16. "Solution structure of the N-terminal domain in human cytokine-induced apoptosis inhibitor anamorsin."Submitted (APR-2008) to the PDB data bank
  17. "Anamorsin is a [2Fe-2S] cluster-containing substrate of the Mia40-dependent mitochondrial protein trapping machinery."Chem. Biol. 18:794-804(2011) [PubMed] [Europe PMC] [Abstract]