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Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2)

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ET; CTP:phosphoethanolamine cytidylyltransferase; Phosphorylethanolamine transferase

Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2)
CCC G537
HGNC 8756
MGI 1915921
PubMed 23354482
RGD 619970
UniProt Q99447
Phosphatidylethanolamine (PtdEtn) is a major membrane phospholipid in both prokaryotic and eukaryotic cells. In the PtdEtn biosynthetic pathway, the enzyme CTP-phosphoethanolamine cytidylyltransferase (ET) catalyzes the formation of CDP-ethanolamine from ethanolamine.
Expression of PCYT2 in yeast ect1 mutants restored ET activity. The sequence of the predicted 389-amino acid PCYT2 protein is 36% identical to that of the yeast ECT1 gene product. Northern blot analysis revealed that PCYT2 is expressed as an approximately 2-kb mRNA in various tissues, with the strongest expression in liver, heart, and skeletal muscle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2) ELISA Kit Customized Service Offer
  1. "Cloning of a human cDNA for CTP-phosphoethanolamine cytidylyltransferase by complementation in vivo of a yeast mutant."J. Biol. Chem. 272:9567-9572(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "Human CTP:phosphoethanolamine cytidylyltransferase."Submitted (JUL-2011) to the PDB data bank