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Solute Carrier Family 25, Member 2 (SLC25A2)

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ORNT2; Ornithine Transporter,Mitochondrial 2

Solute Carrier Family 25, Member 2 (SLC25A2)
CCC G581
HGNC 22921
MGI 2137907
PubMed 11004452
RGD 1310667
UniProt Q9BXI2
The ORNT2 gene encodes a mitochondrial ornithine transporter that is 88% identical to that encoded by ORNT1. Northern blot analysis and PCR demonstrated highest ORNT2 expression in liver, with less significant expression in pancreas and minimal expression in kidney.Immunofluorescence analysis of transiently transfected fibroblasts from control and hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH) patients demonstrated that ORNT2 is localized to mitochondria.
The ORNT2 cDNA is 1,412 bp, with a 186-bp 5-prime untranslated region, a 903-bp open reading frame, and a 323-bp 3-prime untranslated region. It contains a variant polyadenylation signal (CATAA) 18 bases before the terminal poly(A)

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 25, Member 2 (SLC25A2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 25, Member 2 (SLC25A2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 25, Member 2 (SLC25A2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 25, Member 2 (SLC25A2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 25, Member 2 (SLC25A2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 25, Member 2 (SLC25A2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 25, Member 2 (SLC25A2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 25, Member 2 (SLC25A2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 25, Member 2 (SLC25A2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 25, Member 2 (SLC25A2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 25, Member 2 (SLC25A2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 25, Member 2 (SLC25A2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 25, Member 2 (SLC25A2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 25, Member 2 (SLC25A2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 25, Member 2 (SLC25A2) ELISA Kit Customized Service Offer
  1. "Comparative DNA sequence analysis of mouse and human protocadherin gene clusters."Genome Res. 11:389-404(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and characterization of human ORNT2: a second mitochondrial ornithine transporter that can rescue a defective ORNT1 in patients with the hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, a urea cycle disorder."Mol. Genet. Metab. 79:257-271(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]