Solute Carrier Family 17, Member 3 (SLC17A3)
[Edit]NPT4; Sodium Phosphate Cotransporter 4; Na(+)/PI cotransporter 4; Sodium-dependent phosphate transport protein 4
By direct cDNA selection, followed by database analysis and screening of human brain, liver, and testis cDNA libraries, Ruddy et al. (1997) cloned SLC17A3, which they called NPT4. The 401-amino acid protein has 4 potential transmembrane domains. Northern blot analysis revealed that SLC17A3 is expressed in liver and kidney, and RT-PCR analysis showed expression in small intestine, liver, kidney, and testis.
Melis et al. (2004) localized NPT4 expression in COS-1 cells to the endoplasmic reticulum by immunofluorescence.Melis et al. (2004) determined that the SLC17A3 gene contains 10 exons.By genomic sequence analysis, Ruddy et al. (1997) mapped the SLC17A3 gene to chromosome 6p21.3.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Solute Carrier Family 17, Member 3 (SLC17A3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 17, Member 3 (SLC17A3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Solute Carrier Family 17, Member 3 (SLC17A3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Solute Carrier Family 17, Member 3 (SLC17A3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Solute Carrier Family 17, Member 3 (SLC17A3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Solute Carrier Family 17, Member 3 (SLC17A3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 17, Member 3 (SLC17A3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Solute Carrier Family 17, Member 3 (SLC17A3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Solute Carrier Family 17, Member 3 (SLC17A3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Solute Carrier Family 17, Member 3 (SLC17A3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Solute Carrier Family 17, Member 3 (SLC17A3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 17, Member 3 (SLC17A3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Solute Carrier Family 17, Member 3 (SLC17A3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Solute Carrier Family 17, Member 3 (SLC17A3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Solute Carrier Family 17, Member 3 (SLC17A3) | ELISA Kit Customized Service Offer |
- "A 1.1-Mb transcript map of the hereditary hemochromatosis locus."Genome Res. 7:441-456(1997) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "NPT4, a new microsomal phosphate transporter: mutation analysis in glycogen storage disease type Ic."J. Inherit. Metab. Dis. 27:725-733(2004) [PubMed] [Europe PMC] [Abstract]
- "Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate." J. Biol. Chem. 285:35123-35132(2010) [PubMed] [Europe PMC] [Abstract]