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RNA Binding Motif Protein, X-Linked (RBMX)

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RBMXP1; HNRPG; RBMXRT; RNMX; Heterogeneous Nuclear Ribonucleoprotein G; Glycoprotein p43

RNA Binding Motif Protein, X-Linked (RBMX)
CCC G646
HGNC 9910
MGI 1343044
PubMed 22344029
RGD 1565256
UniProt P38159
Wiki RBMX
RBMX belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. RBMYis widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified but their biological nature has not been determined.TRA2B have opposite effects upon the incorporation of several exons, and that both are capable of acting as either an activator or a repressor. HNRNPG acts via a specific sequence to repress the skeletal muscle-specific exon (SK) of human slow skeletal alpha-tropomyosin (TPM3), and stimulates inclusion of the alternative nonmuscle exon.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein, X-Linked (RBMX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein, X-Linked (RBMX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein, X-Linked (RBMX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein, X-Linked (RBMX) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein, X-Linked (RBMX) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein, X-Linked (RBMX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein, X-Linked (RBMX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein, X-Linked (RBMX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein, X-Linked (RBMX) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein, X-Linked (RBMX) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein, X-Linked (RBMX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein, X-Linked (RBMX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein, X-Linked (RBMX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein, X-Linked (RBMX) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein, X-Linked (RBMX) ELISA Kit Customized Service Offer
  1. "hnRNP G: sequence and characterization of a glycosylated RNA-binding protein."Nucleic Acids Res. 21:4210-4217(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Expression and conservation of processed copies of the RBMX gene."Mamm. Genome 12:538-545(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. , Submitted (JUL-2007) to UniProtKB
  7. "T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis."Hum. Mol. Genet. 8:959-969(1999) [PubMed] [Europe PMC] [Abstract]
  8. "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis."RNA 8:426-439(2002) [PubMed] [Europe PMC] [Abstract]
  9. "hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1."Hum. Mol. Genet. 11:2037-2049(2002) [PubMed] [Europe PMC] [Abstract]
  10. "HnRNP G and Tra2beta: opposite effects on splicing matched by antagonism in RNA binding."Hum. Mol. Genet. 12:1337-1348(2003) [PubMed] [Europe PMC] [Abstract]
  11. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  12. "Heterogeneous nuclear ribonucleoprotein G shows tumor suppressive effect against oral squamous cell carcinoma cells."Clin. Cancer Res. 12:3222-3228(2006) [PubMed] [Europe PMC] [Abstract]
  13. "The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G."Biochim. Biophys. Acta 1774:1339-1350(2007) [PubMed] [Europe PMC] [Abstract]
  14. "An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release."Biochem. Biophys. Res. Commun. 371:505-509(2008) [PubMed] [Europe PMC] [Abstract]
  15. "hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip."Biochem. Biophys. Res. Commun. 372:880-885(2008) [PubMed] [Europe PMC] [Abstract]
  16. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  17. "Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA."J. Biol. Chem. 284:14303-14315(2009) [PubMed] [Europe PMC] [Abstract]
  18. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  19. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  20. "Novel domains in the hnRNP G/RBMX protein with distinct roles in RNA binding and targeting nascent transcripts."Nucleus 1:109-122(2010) [PubMed] [Europe PMC] [Abstract]
  21. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  22. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  23. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  24. "NMR structure of the first RRM domain of the protein RBM39 from Homo sapiens."Submitted (MAR-2014) to the PDB data bank