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RNA Binding Motif Protein 38 (RBM38)

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HSRNASEB; SEB4D; Seb4B; RNPC1; RNA-Binding Region(RNP1,RRM)Containing 1; CLL-associated antigen KW-5; ssDNA-binding protein SEB4

RNA Binding Motif Protein 38 (RBM38)
CCC G647
HGNC 15818
MGI 1889294
PubMed 22027593
RGD 1308503
UniProt Q9H0Z9
Using microarray analysis to identify potential p53 (TP53) target genes in human cell lines, Shu et al. (2006) identified and cloned 2 variants of RBM38, which they called RNPC1a and RNPC1b. The deduced proteins contain 239 and 121 amino acids, respectively, and both contain an identical N-terminal canonical RNA recognition motif made up of 2 conserved submotifs, RNP1 and RNP2. Immunofluorescence analysis localized both proteins in the perinuclear membrane and cytosol, with a larger proportion of RNPC1b localized to the cytosol than the nucleus.Both RNPC1a and RNPC1b were also induced by several p63 (TP63) and p73 (TP73) isoforms. RNPC1 expression was induced by DNA-damaging agents in cells expressing wildtype p53, but not in cells lacking p53 expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG647Hu01 Recombinant RNA Binding Motif Protein 38 (RBM38) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG647Hu01 Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38) WB; IHC; ICC; IP.
MAG647Hu21 Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38) WB; IHC; ICC; IP.
Assay Kits SEG647Hu ELISA Kit for RNA Binding Motif Protein 38 (RBM38) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein 38 (RBM38) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein 38 (RBM38) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein 38 (RBM38) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein 38 (RBM38) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein 38 (RBM38) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein 38 (RBM38) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein 38 (RBM38) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein 38 (RBM38) ELISA Kit Customized Service Offer
  1. "Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX."Blood 100:2123-2131(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript."Genes Dev. 20:2961-2972(2006) [PubMed] [Europe PMC] [Abstract]
  5. "ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing."Mol. Cell 33:591-601(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Solution structure of the RNA recognition motif in RNA-binding region containing protein 1."Submitted (MAY-2005) to the PDB data bank