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ZNF200 contains 5 tandem Kruppel-like C2H2 domains, each of which binds a zinc ion to form a globular domain. Western blot analysis detected endogenous ZNF200 at an apparent molecular mass of 50 kD in human embryonic kidney cells. Epitope-tagged ZNF200 colocalized with G9A (EHMT2) in most areas of the nucleus as discrete speckles. During metaphase, the 2 proteins colocalized outside of mitotic chromosomes.
During genomic sequencing and exon trapping in the chromosomal region around the familial Mediterranean fever locus (MEFV), the French FMF Consortium (1997) identified a novel gene encoding a zinc finger protein. The authors amplified all 5 exons from a human liver cDNA library. The open reading frame encodes a 394-amino acid polypeptide.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Zinc Finger Protein 200 (ZNF200) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Zinc Finger Protein 200 (ZNF200) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Zinc Finger Protein 200 (ZNF200) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Zinc Finger Protein 200 (ZNF200) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Zinc Finger Protein 200 (ZNF200) | ELISA Kit Customized Service Offer |
- "Identification of two Kruppel-related zinc finger genes (ZNF200 and ZNF210) from human chromosome 16p13.3."Genomics 53:97-103(1998) [PubMed] [Europe PMC] [Abstract]
- "A candidate gene for familial Mediterranean fever." Nat. Genet. 17:25-31(1997) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]