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G Protein Coupled Receptor 109B (GPR109B)

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HCAR3; NIACR2; HM74; HCA3; HM74B; PUMAG; Puma-g; Niacin Receptor 2; Nicotinic acid receptor 2; Hydroxycarboxylic acid receptor 3

G Protein Coupled Receptor 109B (GPR109B)
CCC G711
HGNC 16824
PubMed 19237584
UniProt P49019
Wiki NIACR2
Chemokine receptors are members of the 7-transmembrane, G protein-coupled receptor (GPCR) family that recognize small proteins responsible for the directed migration of specific cell types.
Sequence analysis predicted that the 387-amino acid, GPCR-type protein has significant homology to the B2 bradykinin receptor (BDKRB2) and to the thrombin receptor (F2R). Northern blot analysis revealed expression of a 2.3-kb HM74 transcript in peripheral blood mononuclear cells and neutrophils.The HM74 protein is a potential 7 transmembrane-spanning receptor that shares 96% identity with HM74A (GPR109A). HM74 expression in spleen, followed by lymphocytes and adipose tissue. Heart, placenta, prostate, and bone marrow showed lower expression, and little to no expression was detected in all other tissues examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG711Hu01 Recombinant G Protein Coupled Receptor 109B (GPR109B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAG711Hu21 Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) WB; IHC; ICC; IP.
PAG711Hu01 Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) WB; IHC; ICC; IP.
Assay Kits SEG711Hu ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) Enzyme-linked immunosorbent assay for Antigen Detection.
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