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G Protein Coupled Receptor 89A (GPR89A)

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UNQ192; GPHRA; GPR89; SH120; Golgi pH regulator A; Putative MAPK-activating protein PM01; Putative NF-kappa-B-activating protein 90

G Protein Coupled Receptor 89A (GPR89A)
CCC G746
HGNC 31984
PubMed 11042152
UniProt B7ZAQ6
Wiki GPR89B
GPR89A is a nearly identical copy of the GPR89B gene. Hartz (2009) mapped the GPR89A gene to chromosome 1q21.1 based on an alignment of the GPR89A sequence with the genomic sequence and determined that the GPR89A gene is centromeric to the GPR89B gene on chromosome 1q21.1.
G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, and animals. The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters, and vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases, and are also the target of approximately 30% of all modern medicinal drugs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Coupled Receptor 89A (GPR89A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Coupled Receptor 89A (GPR89A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Coupled Receptor 89A (GPR89A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Coupled Receptor 89A (GPR89A) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Coupled Receptor 89A (GPR89A) ELISA Kit Customized Service Offer
  1. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism." Nat. Commun. 5:3650-3650(2014) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways."Oncogene 22:3307-3318(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus."Nat. Cell Biol. 10:1135-1145(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis."Cell 136:136-148(2009) [PubMed] [Europe PMC] [Abstract]