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TNF Receptor Associated Factor 6 (TRAF6)

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RNF85; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer

TNF Receptor Associated Factor 6 (TRAF6)
CCC G751
HGNC 12036
MGI 108072
PubMed 24492375
RGD 1306853
UniProt Q9Y4K3
Wiki TRAF6
TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG751Hu01 Recombinant TNF Receptor Associated Factor 6 (TRAF6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG751Hu01 Polyclonal Antibody to TNF Receptor Associated Factor 6 (TRAF6) WB,IHC,ICC/IF
MAG751Hu21 Monoclonal Antibody to TNF Receptor Associated Factor 6 (TRAF6) WB; IHC; ICC; IP.
Assay Kits SEG751Hu ELISA Kit for TNF Receptor Associated Factor 6 (TRAF6) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG751Mu01 Recombinant TNF Receptor Associated Factor 6 (TRAF6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG751Mu01 Polyclonal Antibody to TNF Receptor Associated Factor 6 (TRAF6) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for TNF Receptor Associated Factor 6 (TRAF6) CLIA Kit Customized Service Offer
n/a ELISA Kit for TNF Receptor Associated Factor 6 (TRAF6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TNF Receptor Associated Factor 6 (TRAF6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TNF Receptor Associated Factor 6 (TRAF6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TNF Receptor Associated Factor 6 (TRAF6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TNF Receptor Associated Factor 6 (TRAF6) CLIA Kit Customized Service Offer
n/a ELISA Kit for TNF Receptor Associated Factor 6 (TRAF6) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG751Ga01 Recombinant TNF Receptor Associated Factor 6 (TRAF6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to TNF Receptor Associated Factor 6 (TRAF6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TNF Receptor Associated Factor 6 (TRAF6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TNF Receptor Associated Factor 6 (TRAF6) CLIA Kit Customized Service Offer
n/a ELISA Kit for TNF Receptor Associated Factor 6 (TRAF6) ELISA Kit Customized Service Offer
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