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Transforming Growth Factor Beta Regulator 4 (TbRG4)

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CPR2; FASTKD4; FAST kinase domain-containing protein 4; Cell cycle progression restoration protein 2

Transforming Growth Factor Beta Regulator 4 (TbRG4)
CCC G792
HGNC 17443
MGI 1100868
PubMed 18255060
RGD 1309737
UniProt Q969Z0
Wiki TBRG4
By screening a hepatoma cDNA expression library for clones that could block mating pheromone-induced G1 arrest in yeast, Edwards et al. (1997) cloned TBRG4, which they called CPR2. The deduced protein contains multiple putative leucine zipper domains characteristic of transcription factors.
By sequencing clones obtained from a size-fractionated human brain cDNA library, Nagase et al. (1999) cloned TBRG4, which they designated KIAA0948. The transcript contains several repetitive elements in the 3-prime untranslated region. The deduced 521-amino acid protein shares significant similarity with rat Cpr2. RT-PCR ELISA detected moderate expression in ovary, and little to no expression in all other tissues and specific brain regions examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transforming Growth Factor Beta Regulator 4 (TbRG4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transforming Growth Factor Beta Regulator 4 (TbRG4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transforming Growth Factor Beta Regulator 4 (TbRG4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transforming Growth Factor Beta Regulator 4 (TbRG4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transforming Growth Factor Beta Regulator 4 (TbRG4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transforming Growth Factor Beta Regulator 4 (TbRG4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transforming Growth Factor Beta Regulator 4 (TbRG4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transforming Growth Factor Beta Regulator 4 (TbRG4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transforming Growth Factor Beta Regulator 4 (TbRG4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transforming Growth Factor Beta Regulator 4 (TbRG4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transforming Growth Factor Beta Regulator 4 (TbRG4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transforming Growth Factor Beta Regulator 4 (TbRG4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transforming Growth Factor Beta Regulator 4 (TbRG4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transforming Growth Factor Beta Regulator 4 (TbRG4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transforming Growth Factor Beta Regulator 4 (TbRG4) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
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  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Human CPR (cell cycle progression restoration) genes impart a Far-phenotype on yeast cells."Genetics 147:1063-1076(1997) [PubMed] [Europe PMC] [Abstract]
  6. "Pig whey acidic protein gene is surrounded by two ubiquitously expressed genes."Biochim. Biophys. Acta 1627:7-14(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]