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Lysine Specific Demethylase 2A (KDM2A)

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FBXL11; FBL11; LILINA; FBL7; CXXC8; JHDM1A; F-Box And Leucine-Rich Repeat Protein 11; CXXC-type zinc finger protein 8; Jumonji C Domain-Containing Histone Demethylase 1A

Lysine Specific Demethylase 2A (KDM2A)
CCC G804
HGNC 13606
MGI 1354736
PubMed 20379134
RGD 1309419
UniProt Q9Y2K7
Wiki KDM2A
KDM2A encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.
The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats. Alternative splicing results in multiple transcript variants.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Specific Demethylase 2A (KDM2A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Specific Demethylase 2A (KDM2A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Specific Demethylase 2A (KDM2A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Specific Demethylase 2A (KDM2A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Specific Demethylase 2A (KDM2A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Specific Demethylase 2A (KDM2A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Specific Demethylase 2A (KDM2A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Specific Demethylase 2A (KDM2A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Specific Demethylase 2A (KDM2A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Specific Demethylase 2A (KDM2A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lysine Specific Demethylase 2A (KDM2A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lysine Specific Demethylase 2A (KDM2A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lysine Specific Demethylase 2A (KDM2A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lysine Specific Demethylase 2A (KDM2A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lysine Specific Demethylase 2A (KDM2A) ELISA Kit Customized Service Offer
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  11. "KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state."Cell Cycle 7:3539-3547(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  13. "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
  14. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  16. "CpG islands recruit a histone H3 lysine 36 demethylase."Mol. Cell 38:179-190(2010) [PubMed] [Europe PMC] [Abstract]
  17. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  18. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  19. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]