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Zinc And Ring Finger Protein 3 (ZNRF3)

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RNF203; E3 ubiquitin-protein ligase ZNRF3

Zinc And Ring Finger Protein 3 (ZNRF3)
CCC G867
HGNC 18126
MGI 3039616
PubMed 22575959
UniProt Q9ULT6
By sequencing clones obtained from a human brain cDNA library, Hirosawa et al. (1999) cloned ZNRF3, which they designated KIAA1133.
The transcript contains a repetitive element in its 3-prime region, and the deduced protein contains 550 amino acids. RT-PCR ELISA detected moderate expression of ZNRF3 in nearly all tissues examined, including adult and fetal brain and all specific adult brain regions. Expression was highest in kidney.
Hartz (2008) mapped the ZNRF3 gene to chromosome 22q12.1 based on an alignment of the ZNRF3 sequence with the genomic sequence (build 36.1).The displayed sequence is further processed into a mature form.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc And Ring Finger Protein 3 (ZNRF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc And Ring Finger Protein 3 (ZNRF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc And Ring Finger Protein 3 (ZNRF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc And Ring Finger Protein 3 (ZNRF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc And Ring Finger Protein 3 (ZNRF3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc And Ring Finger Protein 3 (ZNRF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc And Ring Finger Protein 3 (ZNRF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc And Ring Finger Protein 3 (ZNRF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc And Ring Finger Protein 3 (ZNRF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc And Ring Finger Protein 3 (ZNRF3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain."DNA Res. 6:329-336(1999) [PubMed] [Europe PMC] [Abstract]
  4. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  5. "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner."Nature 485:195-200(2012) [PubMed] [Europe PMC] [Abstract]