Trehalase (TREH)
[Edit]TRE; TREA; Brush Border Membrane Glycoprotein; Alpha,Alpha-Trehalase; Alpha,Alpha-Trehalose Glucohydrolase
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Trehalose (1-alpha-D-glucopyranosyl alpha-D-glucopyranoside) is widely distributed in nature, being the storage disaccharide of fungi and the blood sugar of insects. Trehalase (EC 3.2.1.28) is an intrinsic glycoprotein of the small intestine and renal brush border membranes that hydrolyzes trehalose to 2 glucose molecules.
The deduced 583-amino acid protein has a calculated molecular mass of 66.6 kD. It has an N-terminal signal peptide, 5 potential N-glycosylation sites, and a C-terminal hydrophobic region for glycosylphosphatidylinositol (GPI) attachment. Northern blot analysis detected a 2.0-kb transcript mainly in kidney, liver, and small intestine.The trehalase signature sequence from amino acids 162 to 175 of mouse Treh shares 100% identity with the corresponding region in human TREH.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG871Hu01 | Recombinant Trehalase (TREH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAG871Hu01 | Polyclonal Antibody to Trehalase (TREH) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Trehalase (TREH) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Trehalase (TREH) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG871Mu01 | Recombinant Trehalase (TREH) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPG871Mu02 | Recombinant Trehalase (TREH) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| EPG871Mu61 | Eukaryotic Trehalase (TREH) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APG871Mu61 | Active Trehalase (TREH) | Cell culture; Activity Assays. | |
| Antibodies | PAG871Mu01 | Polyclonal Antibody to Trehalase (TREH) | WB; IHC; ICC; IP. |
| PAG871Mu02 | Polyclonal Antibody to Trehalase (TREH) | WB; IHC; ICC; IP. | |
| Assay Kits | SEG871Mu | ELISA Kit for Trehalase (TREH) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Trehalase (TREH) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Trehalase (TREH) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Trehalase (TREH) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Trehalase (TREH) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Trehalase (TREH) | ELISA Kit Customized Service Offer |
- "Molecular cloning, sequencing and expression of cDNA encoding human trehalase."Gene 202:69-74(1997) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Human trehalase: characterization, localization, and its increase in urine by renal proximal tubular damage."Nephron 73:179-185(1996) [PubMed] [Europe PMC] [Abstract]