≡

Voltage Dependent Anion Channel Protein 3 (VDAC3)

[Edit]

HD-VDAC3; Outer mitochondrial membrane protein porin 3

Voltage Dependent Anion Channel Protein 3 (VDAC3)
CCC G900
HGNC 12674
MGI 106922
PubMed 23388454
RGD 621577
UniProt Q9Y277
Wiki VDAC3
VDAC3 belongs to a group of mitochondrial membrane channels involved in translocation of adenine nucleotides through the outer membrane. These channels may also function as a mitochondrial binding site for hexokinase and glycerol kinase.
The deduced 283-amino acid protein is 67% identical to VDAC1 and 73% identical to VDAC2. Northern blot analysis detected a 1.4-kb transcript in all tissues examined, with high expression in testis. SDS-PAGE of transfected COS-1 cells showed epitope-tagged VDAC3 at about 30 kD.
RNA interference-mediated knockdown of VDAC2 or VDAC3 caused resistance to erastin, implicating these 2 VDAC isoforms in the mechanism of action of erastin.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Voltage Dependent Anion Channel Protein 3 (VDAC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Voltage Dependent Anion Channel Protein 3 (VDAC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Voltage Dependent Anion Channel Protein 3 (VDAC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Voltage Dependent Anion Channel Protein 3 (VDAC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Voltage Dependent Anion Channel Protein 3 (VDAC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Voltage Dependent Anion Channel Protein 3 (VDAC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Voltage Dependent Anion Channel Protein 3 (VDAC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Voltage Dependent Anion Channel Protein 3 (VDAC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Voltage Dependent Anion Channel Protein 3 (VDAC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Voltage Dependent Anion Channel Protein 3 (VDAC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Voltage Dependent Anion Channel Protein 3 (VDAC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Voltage Dependent Anion Channel Protein 3 (VDAC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Voltage Dependent Anion Channel Protein 3 (VDAC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Voltage Dependent Anion Channel Protein 3 (VDAC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Voltage Dependent Anion Channel Protein 3 (VDAC3) ELISA Kit Customized Service Offer
  1. "Isolation of a novel human voltage-dependent anion channel gene."Eur. J. Hum. Genet. 6:337-340(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning."Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Revised fine mapping of the human voltage-dependent anion channel loci by radiation hybrid analysis."Mamm. Genome 10:1041-1042(1999) [PubMed] [Europe PMC] [Abstract]
  5. "The tissue-specific, alternatively spliced single ATG exon of the type 3 voltage-dependent anion channel gene does not create a truncated protein isoform in vivo."Mol. Genet. Metab. 70:69-74(2000) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria."Nat. Cell Biol. 17:160-169(2015) [PubMed] [Europe PMC] [Abstract]